Browsing by Author "Ganley-Leal, Lisa"
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CD23b isoform expression in human schistosomiasis identifies a novel subset of activated B cells
Onguru, Daniel O.; Liang, YanMei; Elliot, Jennifer; Mwinzi, Pauline; Ganley-Leal, Lisa (American Society for Microbiology, 2011)Resistance to schistosomiasis is associated with increased levels of serum parasite-specific IgE. IgE exerts its functions through its cellular receptors, FcεRI and FcεRII/CD23; however, its functional significance requires ... -
Human schistosomiasis is associated with endotoxemia and toll-like receptor 2- and 4-Bearing B Cells
Onguru, Daniel O.; Liang, YanMei; Griffith, Qyana; Nikolajczyk, Barbara; Mwinzi, Pauline; Ganley-Leal, Lisa (The American Society of Tropical Medicine and Hygiene, 2010)Schistosomiasis is caused by parasitic trematodes. Individuals can accumulate hundreds of intravascular worms, which secrete a myriad of antigenic molecules into the bloodstream. Some of these molecules suppress immunity ...