Browsing by Author "Mwinzi, Pauline"

Now showing items 1-3 of 3

    • Bioactive carbazole alkaloids from Alysicarpus ovalifolius (Schumach) 

      Ochung, Angeline A.; Manguro, Lawrence Arot O.; Owuor, Phillip O.; Jondiko, Isaac O.; Nyunja, Regina A.; Akala, Hosea; Mwinzi, Pauline; Opiyo, Sylvia A. (The Korean Society for Applied Biological Chemistry, 2015-08-19)
      Phytochemical and biological evaluation of the stem bark of Alysicarpus ovalifolius led to the isolation of three carbazole alkaloids identified as mohanimbine (1), koenimbine (2) and koenidine (3) along with quercetin ...

    • CD23b isoform expression in human schistosomiasis identifies a novel subset of activated B cells 

      Onguru, Daniel O.; Liang, YanMei; Elliot, Jennifer; Mwinzi, Pauline; Ganley-Leal, Lisa (American Society for Microbiology, 2011)
      Resistance to schistosomiasis is associated with increased levels of serum parasite-specific IgE. IgE exerts its functions through its cellular receptors, FcεRI and FcεRII/CD23; however, its functional significance requires ...

    • Human schistosomiasis is associated with endotoxemia and toll-like receptor 2- and 4-Bearing B Cells 

      Onguru, Daniel O.; Liang, YanMei; Griffith, Qyana; Nikolajczyk, Barbara; Mwinzi, Pauline; Ganley-Leal, Lisa (The American Society of Tropical Medicine and Hygiene, 2010)
      Schistosomiasis is caused by parasitic trematodes. Individuals can accumulate hundreds of intravascular worms, which secrete a myriad of antigenic molecules into the bloodstream. Some of these molecules suppress immunity ...