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Human schistosomiasis is associated with endotoxemia and toll-like receptor 2- and 4-Bearing B Cells
(The American Society of Tropical Medicine and Hygiene, 2010)
Schistosomiasis is caused by parasitic trematodes. Individuals can accumulate hundreds of intravascular worms, which secrete a myriad of antigenic molecules into the bloodstream. Some of these molecules suppress immunity ...
CD23-Bound IgE augments and dominates recall responses through human Naive B cells
(American association of immunology, 2010)
Human peripheral blood BCRμ+ B cells express high levels of CD23 and circulate preloaded with IgE. The Ag specificity of CD23-bound IgE presumably differs from the BCR and likely reflects the Ag-specific mix of free serum ...