Browsing School of Biological, Physical, Mathematics & Actuarial Sciences by Author "Swai, Hulda"

Now showing items 1-3 of 3

    • Development, characterization and antimalarial efficacy of dihydroartemisinin loaded solid lipid nanoparticles 

      Omwoyo, Wesley N.; Melariri, Paula; Gathirwa, Jeremiah W.; Oloo, Florence; Mahanga, Geoffrey M.; Ogutu, Bernhards; Swai, Hulda (ELSEVIER, 2016-04)
      Effective use of dihydroartemisinin (DHA) is limited by poor water-solubility, poor pharmacokinetic profile and unsatisfactory clinical outcome especially in monotherapy. To reduce such limitations, we reformulated DHA ...

    • Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles 

      Omwoyo, Wesley Nyaigoti; Ogutu, Bernhards; Oloo, Florence; Swai, Hulda; Kalombo, Lonji; Melariri, Paula; Mahanga, Geoffrey M.; Gathirwa, Jeremiah Waweru (PMC, 2014-08-11)
      Primaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- ...

    • Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles 

      Omwoyo, Wesley Nyaigoti; Ogutu, Bernhards; Oloo, Florence; Swai, Hulda; Kalombo, Lonji; Melariri, Paula; Mahanga, Geoffrey Maroa; Gathirwa, Jeremiah Waweru (International Journal of nanomedicine, 2014-08-11)
      Primaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- ...