School of Health Sciences: Recent submissions
Now showing items 161-180 of 180
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yphim Vi vaccine against typhoid fever: A clinical trial in Kenya
(PubMed, 1995)Safety, tolerance and immunogenicity of the purified Vi polysaccharide vaccine (Typhim Vi) against typhoid fever was evaluated in primary school children aged 5-15 years. A total of 435 children were vaccinated, each with ... -
Bancroftian filariasis in Kwale District of Kenya. III. Quantification of the IgE response in selected individuals from an endemic community.
(PubMed, 1995)One hundred and sixty-two individuals from a community in Kwale District, Kenya, endemic for bancroftian filariasis, were selected for a study on the IgE response to filarial antigen (prepared from adult Brugia pahangi). ... -
Bancroftian filariasis in Kwale District of Kenya. I. Clinical and parasitological survey in an endemic community
(PubMed, 1994-04)A cross-sectional parasitological and clinical survey for Wuchereria bancrofti infection was carried out in an endemic community of south-eastern Kenya, to obtain background epidemiological information for detailed serological ... -
Protozoan infections and HIV-1 infection: a review.
(PubMed, 1992)Reactivation of latent infection is the principal mechanism relating Toxoplasma gondii and Pneumocystis carinii to HIV. Less common is reactivation in Leishmania donovani, Trypanosoma cruzi, and microsporidian infections. ... -
A study of the efficacy and safety of albendazole (Zentel) in the treatment of intestinal helmenthiasis in Kenyan children less than 2 years of age
(PubMed, 1989-03)One hundred children comprising of 57 males and 43 females aged between 8 and 24 months entered the study. 46 children had single and 54 children had multiple helminth infections. All children received albendazole 200 mg ... -
Comparison of four nitroimidazole compounds for treatment of symptomatic amoebiasis in Kenya.
(PubMed, 1989)Four antiamoebic drugs currently used in many Kenyan hospitals and health centres were compared for their efficacy on symptomatic luminal amoebiasis in Kiambu, Kilifi, and Machakos hospitals during this study. The drugs ... -
Pathogenicity of Trichomonas hominis in Kenya
(1988-08)An in vitro study of the antinematodal action of two groups of compounds which act on the receptor complex of the inhibitory neurotransmitter, Gamma-aminobutyric acid (GABA) in mammalian systems is described. The compounds, ... -
The occurrence of Cryptosporidium oocysts in faecal samples submitted for routine examination at Kenyatta National Hospital
(Taylor & Francis, 1989-12)One hundred and thirty-three loose or diarrhoeic stool specimens from patients admitted at Kenyatta National Hospital were examined for cryptosporidiosis. Oocysts were detected in 5(3.8%) of the total in which Cryptosporidium ... -
The potential of schistosomal skin test as a diagnostic method in the detection of schistosomiasis.
(NCBI, 1989-07)One hundred and sixty seven volunteer medical students were exposed to intradermal skin tests for schistosomiasis. 35(21%) were positive. On further screening using routine stool and urine examinations, only 11(6.6%) were ... -
Effects of HIV-1 infection on malaria parasitemia in milo sub-location, western Kenya
(BMC, 2015)Malaria and HIV infections are both highly prevalent in sub-Saharan Africa, with HIV-infected patients being at higher risk of acquiring malaria. HIV-1 infection is known to impair the immune response and may increase the ... -
Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): A randomised trial
(The Lancet, 2010-11)Mobile (cell) phone communication has been suggested as a method to improve delivery of health services. However, data on the effects of mobile health technology on patient outcomes in resource-limited settings are limited. ... -
Modeling of liver cancer risk factors and dynamics at community level
(Hikari, 2017)Hepatocellular carcinoma (HCC) is a malignant cancer of the liver arising from uncontrolled multiplication of the abnormal liver cells. It is an ignored public health condition where patients come late to the hospital at ... -
Patterns and trends of malaria morbidity in Western highlands of Kenya
(International Journal of Education and Research, 2013-12)A study of patterns and trends of malaria morbidity was conducted in Kericho district in Kenya western highlands prone to occurrences of malaria epidemics. Kericho district supports small scale and large scale tea farming, ... -
Effect of dietary carbohydrate sources on the growth of Oreochromis Niloticus L: A case of Kaaka fish farm, Namutumba district, Eastern Uganda
(European International Journal of Science and Technology, 2014-08)A 16-week field experiment was carried out at Kaaka fish farm in Namutumba district to investigate the effect of dietary carbohydrate sources on the growth performance of Nile tilapia, Oreochromis niloticus L Fish fry of ... -
Changes in b cell populations and Merozoite surface protein-1-specific memory b cell responses after prolonged absence of detectable p. falciparum infection
(PLOS, 2013-05)Clinical immunity to malaria declines in the absence of repeated parasite exposure. However, little is known about how B cell populations and antigen-specific memory B cells change in the absence of P. falciparum infection. ... -
Evolution of the primate trypanolytic factor APOL1
(PNAS, 2014-04-08)ApolipoproteinL1 (APOL1) protects humans and some primates against several African trypanosomes. APOL1 genetic variants strongly associated with kidney disease in African Americans have additional trypanolytic activity ... -
Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants
(The American Society of Human Genetics, 2007-08)Statistical power to detect disease variants can be increased by weighting candidates by their evidence of natural selection. To demonstrate that this theoretical idea works in practice, we performed an association study ... -
Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control
(The American Society of Tropical Medicine and Hygiene, 2007-02-23)Human co-infection with Plasmodium falciparum and helminths is ubiquitous throughout Africa, although its public health significance remains a topic for which there are many unknowns. In this review, we adopted an empirical ... -
Earth-eating and reinfection with intestinal helminths among pregnant and lactating women in western Kenya
(Blackwell Publishing Ltd, 2005-03)We conducted a longitudinal study among 827 pregnant women in Nyanza Province, western Kenya, to determine the effect of earth-eating on geohelminth reinfection after treatment. The women were recruited at a gestational ... -
Schistosoma haematobium and soil-transmitted Helminths in Tana Delta District of Kenya: infection and morbidity patterns in primary schoolchildren from two isolated villages
(BioMed Central, 2016-02-03)Schistosomes and soil-transmitted helminths (STH) (hookworm, Trichuris trichiura and Ascaris lumbricoides) are widely distributed in developing countries where they infect over 230 million and 1.5 billion people, respectively. ...