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Decline in childhood iron deficiency after interruption of malaria transmission in highland Kenya1–3
(AJCN, 2014-07-30)
Background: Achieving optimal iron status in children in malariaendemic areas may increase the risk of malaria. Malaria itself may contribute to iron deficiency, but the impact of an interruption in malaria transmission ...
The Plasmodium falciparum antigen MB2 induces interferon-γ and interleukin-10 responses in adults in malaria endemic areas of Western Kenya
(PMC, 2013)
Background:
MB2 is a novel Plasmodium falciparum antigen of unknown function expressed in pre-erythrocytic and blood stages of infection in the human host. Interferon-gamma (IFN-γ) and interleukin (IL)-10 responses to ...
Antibody Profiles to P. falciparum Antigens over Time Characterize Acute and Long-Term Malaria Exposure in an Area of Low and Unstable Transmission
(The American Society of Tropical Medicine and Hygiene, 2020-12-02)
Prevalence and levels of antibodies to multiple Plasmodium falciparum antigens show promise as tools for estimating malaria exposure. In a highland area of Kenya with unstable transmission, we assessed the presence and ...
Antibody Correlates of Protection from Clinical Plasmodium Falciparum Malaria in an Area of Low and Unstable Malaria Transmission
(The American Society of Tropical Medicine and Hygiene, 2020-12-02)
Immune correlates of protection against clinical malaria are difficult to ascertain in low-transmission areas because of the limited number of malaria cases. We collected blood samples from 5,753 individuals in a Kenyan ...