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Patterns and trends of malaria morbidity in Western highlands of Kenya
(International Journal of Education and Research, 2013-12)
A study of patterns and trends of malaria morbidity was conducted in Kericho district in Kenya
western highlands prone to occurrences of malaria epidemics. Kericho district supports small scale and large scale tea farming, ...
Effects of HIV-1 infection on malaria parasitemia in milo sub-location, western Kenya
(BMC, 2015)
Malaria and HIV infections are both highly prevalent in sub-Saharan Africa, with HIV-infected patients
being at higher risk of acquiring malaria. HIV-1 infection is known to impair the immune response and may increase
the ...
Red blood cell immune complex binding capacity in children with sickle cell trait (HBAS) living in p. falciparum malaria holoendemic region of Western Kenya
(IJTDH, 2012)
Malaria infection leads to the formation of circulating immune complexes (CICs) which have been implicated in the pathogenesis of complicated malaria which includes severe malarial anemia. Children with sickle cell trait ...
Increased complement deposition on red blood cells in children with sickle cell trait
(BJMMR, 2015)
Aims: Immune-mediated mechanism, such as deposition of complement (C3b) on erythrocytes leading to enhanced receptor-mediated uptake by macrophages has been proposed to contribute
partly to the destruction of non-infected ...
Lay knowledge and management of malaria in Baringo County, Kenya
(BMC, 2016)
Background: Malaria, a disease caused by protozoan parasites of the genus Plasmodium and transmitted by female anopheline mosquitoes, is a major cause of morbidity, mortality and loss in productivity in humans. Baringo ...
Perennial transmission of malaria in the low altitude areas of Baringo County, Kenya
(BMC, 2017)
Background: Malaria causes the greatest public health burden in sub-Saharan Africa where high mortality occurs mainly in children under 5 years of age. Traditionally, malaria has been reported mainly in the lowlands endemic ...
Evaluation of three rapid diagnostic test kits in the diagnosis of plasmodium species infections among primary school children in Baringo County, Kenya
(scientific research, 2017)
Background: Due to the difficulty in implementing microscopy-based definitive diagnosis of malaria especially in resource-poor areas, rapid diagnostic test (RDT) kits as alternatives have been developed by different ...
Interferon-γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission
(Peer J, 2017-01-10)
Background
Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as antigen-specific IFN- γ responses are not well characterized.
Methods
IFN- ...
Standardization and validation of a cytometric bead assay to assess antibodies to multiple Plasmodium falciparum recombinant antigens
(BioMed Central Ltd, 2012-12-21)
Background
Multiplex cytometric bead assay (CBA) have a number of advantages over ELISA for antibody testing, but little information is available on standardization and validation of antibody CBA to multiple Plasmodium ...
Decreased prevalence of anemia in highland areas of low malaria transmission after a 1-Year interruption of transmission
(Oxford University Press, 2011-11-03)
Background. Malaria control campaigns have reduced malaria transmission to very low levels in many areas of Africa. Yet the extent to which malaria interruption or elimination might decrease the prevalence of anemia in ...