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Sensitivity of fever for diagnosis of clinical malaria in a Kenyan area of unstable, low malaria transmission
(BMC, 2014-04-30)
Background
Malaria in highland areas of Kenya affects children and adults. Local clinicians include symptoms other than fever when screening for malaria because they believe that fever alone does not capture all cases of ...
Factors associated with default from TB treatment among tuberculosis patients in Busia County
(IJASSH, 2016-08)
Tuberculosis remains a major health problem in many tropical countries, including Kenya. Defaulting from treatment has been an obstacle to treatment management control. Inability to complete the prescribed regimen is quite ...
Decline in childhood iron deficiency after interruption of malaria transmission in highland Kenya1–3
(AJCN, 2014-07-30)
Background: Achieving optimal iron status in children in malariaendemic areas may increase the risk of malaria. Malaria itself may contribute to iron deficiency, but the impact of an interruption in malaria transmission ...
Successful global health research partnerships: What makes them work?
(The American Society of Tropical Medicine and Hygiene, 2016-01)
There are many successful global health research partnerships, but little information is available about what makes them successful. We asked 14 research colleagues from Uganda, Kenya, and the United States who have extensive ...
An ethnic-specific polymorphism in the catalytic subunit of glutamate-cysteine ligase impairs the production of glutathione intermediates in vitro
(ScienceDirect, 2010-09)
Glutathione plays a crucial role in free radical scavenging, oxidative injury, and cellular homeostasis. Previously, we identified a non-synonymous polymorphism (P462S) in the gene encoding the catalytic subunit of ...
Knowledge, practices and perception of health care workers on diagnosis of childhood tuberculosis: a case study of Bureti Sub County, Kericho, Kenya
(INDIAN JOURNAL OF APPLIED RESEARCH, 2018)
Background: Despite the advances in the diagnosis of tuberculosis, effective diagnosis remains a challenge among children. Several countries have rolled out effective diagnostic methods but capacity of health care workers ...
Decrease in numbers of naive and resting B cells in HIV-infected Kenyan adults leads to a proportional increase in total and Plasmodium falciparum–specific atypical memory B cells
(The American Association of Immunologists, Inc., 2017-05-19)
Human immunodeficiency virus type 1 (HIV-1) infection is associated with B cell activation and exhaustion, and hypergammaglobulinemia. How these changes influence B cell responses to coinfections such as malaria is poorly ...
The Plasmodium falciparum antigen MB2 induces interferon-γ and interleukin-10 responses in adults in malaria endemic areas of Western Kenya
(PMC, 2013)
Background:
MB2 is a novel Plasmodium falciparum antigen of unknown function expressed in pre-erythrocytic and blood stages of infection in the human host. Interferon-gamma (IFN-γ) and interleukin (IL)-10 responses to ...
Impact of land use on the distribution and diversity of entomopathogenic nematodes in Embu and Taita Districts, Kenya
(Tropical and Subtropical Agroecosystems, 2010)
Natural entomopathogenic nematodes(EPNs) are considered as potential biological control agents against soil-borne insect pests. This study was conducted to determine the impact of land use on the distribution occurrence ...
Home Based Care Practices Contribute To Delayed Health Care Seeking For Children Under Five Years with Fever in Malaria Endemic Areas of Western Kenya
(International Journal of Development Research, 2019-08)
Delay in care seeking at health facilities for malaria related fever results into mortality of several children under five years. Both hospital and home-based care practices have contributed to delay in seeking care at the ...