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Sensitivity of fever for diagnosis of clinical malaria in a Kenyan area of unstable, low malaria transmission
(BMC, 2014-04-30)
Background
Malaria in highland areas of Kenya affects children and adults. Local clinicians include symptoms other than fever when screening for malaria because they believe that fever alone does not capture all cases of ...
An ethnic-specific polymorphism in the catalytic subunit of glutamate-cysteine ligase impairs the production of glutathione intermediates in vitro
(ScienceDirect, 2010-09)
Glutathione plays a crucial role in free radical scavenging, oxidative injury, and cellular homeostasis. Previously, we identified a non-synonymous polymorphism (P462S) in the gene encoding the catalytic subunit of ...
The Plasmodium falciparum antigen MB2 induces interferon-γ and interleukin-10 responses in adults in malaria endemic areas of Western Kenya
(PMC, 2013)
Background:
MB2 is a novel Plasmodium falciparum antigen of unknown function expressed in pre-erythrocytic and blood stages of infection in the human host. Interferon-gamma (IFN-γ) and interleukin (IL)-10 responses to ...
Perennial transmission of malaria in the low altitude areas of Baringo County, Kenya
(BMC, 2017)
Background
Malaria causes the greatest public health burden in sub-Saharan Africa where high mortality occurs mainly in children under 5 years of age. Traditionally, malaria has been reported mainly in the lowlands endemic ...
Artisanal Fishing Supports Breeding of Malaria Mosquitoes in Western Kenya
(BMC, 2019)
Background: Everyday hundreds of people, mainly men, set out to take part in a vibrant artisanal capture fshing (ACF) industry on Lake Victoria. It is not known whether actions of artisanal fshers, in their unrelenting ...
Innovative Tools and OpenHDS for Health and Demographic Surveillance on Rusinga Island, Kenya
(BMC, 2015-09-01)
Health in low and middle income countries is on one hand characterized by a high burden associated with preventable communicable diseases and on the other hand considered to be under-documented due to improper basic health ...
Spatial Heterogeneity of Malaria Vectors and Malaria Transmission Risk Estimated Using Odour-Baited Mosquito Traps
(BMC- Malaria Journal, 2014-09-22)
Prior to the commencement of a large-scale malaria intervention study on Rusinga Island, western Kenya, intensive baseline surveillance of the mosquito population was performed using odour-baited traps. The survey aimed ...
Malaria Transmission after Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine: A Randomized Trial
(The Journal of Infectious Diseases, 2013-03-06)
Artemisinin-based combination therapy (ACT) reduces the potential for malaria transmission
compared with non-ACTs. It is unclear whether this effect differs between ACTs.
Methods. A total of 298 children (age, 6 months ...
Recurrent Malaria in Kenya: Survival Distribution and Equality of Survival Distribution
(ResearchGate, 2017-12)
Malaria is a leading cause of morbidity and mortality in Kenya, mostly affecting the rural poor, especially young children and pregnant women. Most clinical studies in malaria involve a number of equally important endpoints. ...
Malaria vector species distribution and seasonal population dynamics across varied ecological zones in Baringo County, Kenya
(Journal of Mosquito Research, 2017)
Vector populations fluctuate on a seasonal basis annually. Knowledge on seasonal abundance and distribution of vector species at the local level would improve vector control programmes and contribute to malaria prevention. ...