Red blood cell immune complex binding capacity in children with sickle cell trait (HBAS) living in p. falciparum malaria holoendemic region of Western Kenya

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dc.contributor.author Otieno, Walter
dc.contributor.author Estambale, Benson B.
dc.contributor.author Odera, Michael M.
dc.contributor.author Aluoch, Joash R.
dc.contributor.author Stoute, José A.
dc.date.accessioned 2018-06-27T13:21:29Z
dc.date.available 2018-06-27T13:21:29Z
dc.date.issued 2012
dc.identifier.uri http://www.dtic.mil/dtic/tr/fulltext/u2/a571728.pdf
dc.identifier.uri http://ir.jooust.ac.ke:8080/xmlui/handle/123456789/1341
dc.description http://www.dtic.mil/dtic/tr/fulltext/u2/a571728.pdf en_US
dc.description.abstract Malaria infection leads to the formation of circulating immune complexes (CICs) which have been implicated in the pathogenesis of complicated malaria which includes severe malarial anemia. Children with sickle cell trait (HbAS) are less predisposed to getting severe manifestations of malaria. We carried out a study to determine the competence of the red blood cells (RBCs) of children with HbAS to bind immune complexes (ICs) and compared this with normal hemoglobin (HbAA). en_US
dc.language.iso en en_US
dc.publisher IJTDH en_US
dc.subject Immunity en_US
dc.subject Plasmodium Falciparum en_US
dc.subject Anemias en_US
dc.subject Assaying en_US
dc.subject Children en_US
dc.subject Deoxygenation en_US
dc.subject Erythrocytes en_US
dc.subject Kenya en_US
dc.subject Malaria en_US
dc.subject Pathogenesis en_US
dc.subject Receptor Sites(Physiology) en_US
dc.subject Sickle Cells en_US
dc.title Red blood cell immune complex binding capacity in children with sickle cell trait (HBAS) living in p. falciparum malaria holoendemic region of Western Kenya en_US
dc.type Article en_US


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