Search
Now showing items 1-6 of 6
CD23b isoform expression in human schistosomiasis identifies a novel subset of activated B cells
(American Society for Microbiology, 2011)
Resistance to schistosomiasis is associated with increased levels of serum parasite-specific IgE. IgE exerts its functions through its cellular receptors, FcεRI and FcεRII/CD23; however, its functional significance requires ...
Human schistosomiasis is associated with endotoxemia and toll-like receptor 2- and 4-Bearing B Cells
(The American Society of Tropical Medicine and Hygiene, 2010)
Schistosomiasis is caused by parasitic trematodes. Individuals can accumulate hundreds of intravascular worms, which secrete a myriad of antigenic molecules into the bloodstream. Some of these molecules suppress immunity ...
Effect of climatic variability on malaria trends in Baringo County, Kenya
(spring open.com, 2017)
Background
Malaria transmission in arid and semi-arid regions of Kenya such as Baringo County, is seasonal and often influenced by climatic factors. Unravelling the relationship between climate variables and malaria ...
CD23-Bound IgE augments and dominates recall responses through human Naive B cells
(American association of immunology, 2010)
Human peripheral blood BCRμ+ B cells express high levels of CD23 and circulate preloaded with IgE. The Ag specificity of CD23-bound IgE presumably differs from the BCR and likely reflects the Ag-specific mix of free serum ...
Perennial transmission of malaria in the low altitude areas of Baringo County, Kenya
(BMC, 2017)
Background
Malaria causes the greatest public health burden in sub-Saharan Africa where high mortality occurs mainly in children under 5 years of age. Traditionally, malaria has been reported mainly in the lowlands endemic ...
Determinants of the Uptake of Intermittent Preventive Treatment of Malaria in Pregnancy with Sulphadoxine Pyrimethamine in Sabatia Sub County, Western Kenya
(BMC, 2021)
Annually, 125.2 million pregnant women worldwide risk contracting malaria, including 30.3 million and 1.5 million in Sub-Saharan Africa and Kenya respectively. At least three doses of sulphadoxine pyrimethamine for ...