Recalcitrant lignin compounds inhibit bioethanol production from biomass. The lignin bind cellulose and hemicellulose in biomass suppressing the fermentation process. Current delignification techniques have an average efficiency of 30% hence affecting the economics of bioethanol production from biomass. In the current work, we report a Manganese(II)-Anderson Polyoxometalate salt (Mn(II)-Anderson POM) , one of the discrete anionic metal oxide salts having a unique Lewis base and Lewis acid properties, to degrade lignin in sugar cane cake root stalk biomass. The results show the Mn(II) - Anderson POM salt to degrade lignin up to 46.97% effectively. Furthermore, upon fermentation of the pretreated cake, bioethanol concentration was 42.12% whereas the positive control (NaOH delignification) had bioethanol concentration of 26.9% using a salt concentration of 3% at 50℃ treating it for a duration of 4 hours. An increase in salt concentration from 1%, 2% and 3% gave significant increase in extracted lignin for both NaOH and POM salts pretreated samples. Similar results were obtained when temperature was varied from 30℃, 40℃, 50℃ and 60℃; and also, time from 2hrs, 3hrs and 4hrs. The quantity and quality of bioethanol obtained followed a similar trend. However, it is noted that in all cases, Mn(II)-Anderson Polyoxometalate salts performed better than NaOH pretreated samples. Specifically, an increase in bioethanol quality (46.13%) after pretreatment with Mn(II)-Anderson POM salt at a concentration of 3%, time 4hrs and temperature 60℃ as compared to NaOH (41.3%) at the same pretreatment parameters is noted