School of Health Sciences: Recent submissions
Now showing items 81-100 of 180
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High prevalence of Rickettsia africae variants in Amblyomma variegatum ticks from domestic mammals in rural Western Kenya: Implications for human health
(Mary Ann Liebert, Inc, 2015-10)Tick-borne spotted fever group (SFG) rickettsioses are emerging human diseases caused by obligate intracellular Gram-negative bacteria of the genus Rickettsia. Despite being important causes of systemic febrile illnesses ... -
Strong association between human and animal Brucella seropositivity in a linked study in Kenya, 2012–2013
(The American Society of Tropical Medicine and Hygiene, 2015)Brucellosis is a common bacterial zoonotic infection but data on the prevalence among humans and animals is limited in Kenya. A cross-sectional survey was conducted in three counties practicing different livestock production ... -
Coxiella burnetii in humans, domestic ruminants, and ticks in rural Western Kenya
(The American Society of Tropical Medicine and Hygiene, 2013)We conducted serological surveys for Coxiella burnetii in archived sera from patients that visited a rural clinic in western Kenya from 2007 to 2008 and in cattle, sheep, and goats from the same area in 2009. We also ... -
Molecular detection of Rickettsia felis and Candidatus Rickettsia Asemboensis in fleas from human habitats, Asembo, Kenya
(Mary Ann Liebert, Inc., 2013)The flea-borne rickettsioses murine typhus (Rickettsia typhi) and flea-borne spotted fever (FBSF) (Rickettsia felis) are febrile diseases distributed among humans worldwide. Murine typhus has been known to be endemic to ... -
Spatial distribution and habitat characterization of mosquito species during the dry season along the Mara River and its tributaries, in Kenya and Tanzania
(BMC, 2018)Background: Vector-borne diseases are increasingly becoming a major health problem among communities living along the major rivers of Africa. Although larger water bodies such as lakes and dams have been extensively ... -
Presence and distribution of mosquito larvae predators and factors influencing their abundance along the Mara River, Kenya and Tanzania
(spring open.com, 2014)Among all the malaria controlling measures, biological control of mosquito larvae may be the cheapest and easiest to implement. This study investigated baseline predation of immature mosquitoes by macroinvertebrate predators ... -
Malaria hotspot areas in a highland Kenya site are consistent in epidemic and non-epidemic years and are associated with ecological factors
(BMC, 2006)Background Malaria epidemics in highland areas of East Africa have caused considerable morbidity and mortality in the past two decades. Knowledge of "hotspot" areas of high malaria incidence would allow for focused ... -
Roles and challenges of community health volunteers in community midwifery practice in Siaya county, kenya
(Numid Publishers, 2017)Introduction: One of the objectives of the United Nations Millennium Development Goals (MDGs) was to reduce MMR by an average of 5.5% every year over the period between1990–2015. As a result, the first international meeting ... -
Perception of Cervical Cancer Patients on their Financial Challenges in Western Kenya
(BMC, 2018)The number of cervical cancer cases is reported to increase among women of reproductive age in the recent past with patients facing challenges with care and management of the illness. However, little is known about the ... -
Spatial distribution and habitat characterization of schistosomiasis host snails in lake and land habitats of western Kenya
(John Wiley & Sons, Inc, 2013)Intermediate host snails of schistosomiasis were surveyed in this study to determine their abundance and distribution in the lake and land aquatic habitats of Lake Victoria basin of Kenya. Several sites were sampled at ... -
Participation of fishing communities in neglected tropical disease/HIV co-infection Cohort Studies in Western Kenya
(2014)Background: Fishing communities on the shores of Lake Victoria are at high risk of schistosome infections, and at the same time, also considered at high risk of HIV infection due to factors associated with lifestyle or ... -
Perennial transmission of malaria in the low altitude areas of Baringo County, Kenya
(BMC, 2017)Background Malaria causes the greatest public health burden in sub-Saharan Africa where high mortality occurs mainly in children under 5 years of age. Traditionally, malaria has been reported mainly in the lowlands endemic ... -
Effect of climatic variability on malaria trends in Baringo County, Kenya
(spring open.com, 2017)Background Malaria transmission in arid and semi-arid regions of Kenya such as Baringo County, is seasonal and often influenced by climatic factors. Unravelling the relationship between climate variables and malaria ... -
CD23b isoform expression in human schistosomiasis identifies a novel subset of activated B cells
(American Society for Microbiology, 2011)Resistance to schistosomiasis is associated with increased levels of serum parasite-specific IgE. IgE exerts its functions through its cellular receptors, FcεRI and FcεRII/CD23; however, its functional significance requires ... -
CD23-Bound IgE augments and dominates recall responses through human Naive B cells
(American association of immunology, 2010)Human peripheral blood BCRμ+ B cells express high levels of CD23 and circulate preloaded with IgE. The Ag specificity of CD23-bound IgE presumably differs from the BCR and likely reflects the Ag-specific mix of free serum ... -
Human schistosomiasis is associated with endotoxemia and toll-like receptor 2- and 4-Bearing B Cells
(The American Society of Tropical Medicine and Hygiene, 2010)Schistosomiasis is caused by parasitic trematodes. Individuals can accumulate hundreds of intravascular worms, which secrete a myriad of antigenic molecules into the bloodstream. Some of these molecules suppress immunity ... -
Decline in childhood iron deficiency after interruption of malaria transmission in highland Kenya1–3
(AJCN, 2014-07-30)Background: Achieving optimal iron status in children in malariaendemic areas may increase the risk of malaria. Malaria itself may contribute to iron deficiency, but the impact of an interruption in malaria transmission ... -
The Plasmodium falciparum antigen MB2 induces interferon-γ and interleukin-10 responses in adults in malaria endemic areas of Western Kenya
(PMC, 2013)Background: MB2 is a novel Plasmodium falciparum antigen of unknown function expressed in pre-erythrocytic and blood stages of infection in the human host. Interferon-gamma (IFN-γ) and interleukin (IL)-10 responses to ... -
Decrease in numbers of naive and resting B cells in HIV-infected Kenyan adults leads to a proportional increase in total and Plasmodium falciparum–specific atypical memory B cells
(The American Association of Immunologists, Inc., 2017-05-19)Human immunodeficiency virus type 1 (HIV-1) infection is associated with B cell activation and exhaustion, and hypergammaglobulinemia. How these changes influence B cell responses to coinfections such as malaria is poorly ... -
Impact of land use on the distribution and diversity of entomopathogenic nematodes in Embu and Taita Districts, Kenya
(Tropical and Subtropical Agroecosystems, 2010)Natural entomopathogenic nematodes(EPNs) are considered as potential biological control agents against soil-borne insect pests. This study was conducted to determine the impact of land use on the distribution occurrence ...