School of Health Sciences: Recent submissions
Now showing items 101-120 of 180
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Successful global health research partnerships: What makes them work?
(The American Society of Tropical Medicine and Hygiene, 2016-01)There are many successful global health research partnerships, but little information is available about what makes them successful. We asked 14 research colleagues from Uganda, Kenya, and the United States who have extensive ... -
Decreased prevalence of anemia in highland areas of low malaria transmission after a 1-Year interruption of transmission
(Oxford University Press, 2011-11-03)Background. Malaria control campaigns have reduced malaria transmission to very low levels in many areas of Africa. Yet the extent to which malaria interruption or elimination might decrease the prevalence of anemia in ... -
An ethnic-specific polymorphism in the catalytic subunit of glutamate-cysteine ligase impairs the production of glutathione intermediates in vitro
(ScienceDirect, 2010-09)Glutathione plays a crucial role in free radical scavenging, oxidative injury, and cellular homeostasis. Previously, we identified a non-synonymous polymorphism (P462S) in the gene encoding the catalytic subunit of ... -
Standardization and validation of a cytometric bead assay to assess antibodies to multiple Plasmodium falciparum recombinant antigens
(BioMed Central Ltd, 2012-12-21)Background Multiplex cytometric bead assay (CBA) have a number of advantages over ELISA for antibody testing, but little information is available on standardization and validation of antibody CBA to multiple Plasmodium ... -
Evaluating parental screening tool for developmental milestone in children under five years in rural Western Kenya
(International Journal of Scientific and Research Publications, 2017-07)Background: An estimated 200 million children suffer from developmental delays, most in developing countries. Early diagnosis through screening is key to timely intervention. However, screening tools have not been assessed ... -
The isolation of leishmanial parasites from domestic goats and wild hosts in Kenya and the possible role of goats as reservoirs of leishmaniases
(International Journal of Tropical Insect Science, 2011-09-01)Screening of leishmanial parasites from domestic and wild animals was carried out in Kacheliba, West Pokot District. Spleens and livers of the animals were cultured in NNN diphasic medium. Thin smears of the same tissues ... -
Laboratory tests of oviposition by the African malaria mosquito, Anopheles gambiae, on dark soil as influenced by presence or absence of vegetation
(BMC, 2006-10-12)Background Physical objects like vegetation can influence oviposition by mosquitoes on soil or water substrates. Anopheles gambiae s. l. is generally thought to utilize puddles over bare soil as its prime larval habitat ... -
Comparative study of aminosidine, etophamide and nimorazole, alone or in combination, in the treatment of intestinal amoebiasis in Kenya
(SpringerLink, 1990-05-26)417 patients suffering from intestinal amoebiasis were randomly allocated to 6 different treatment groups in a controlled study in 3 District Hospitals in Kenya. The patients received either aminosidine (A), etophamide ... -
The efficacy of 22,23-dihydroavermectin B1 (ivermectin) acting singly or in combination with a benzodiazepine on microfilariae of Onchocerca species and Brugia pahangi (an in vitro study)
(ELSEVIER, 1989-07)An in vitro study of the antinematodal action of two groups of compounds which act on the receptor complex of the inhibitory neurotransmitter, Gamma-aminobutyric acid (GAGA) in mammalian systems is described. The compounds, ... -
HIV and cervical cancer in Kenya
(International Journal of Gynecology and Obstetrics, 2002-01)Objectives: To determine the effect of the HIV epidemic on invasive cervical cancer in Kenya. Methods: Of the 3902 women who were diagnosed with reproductive tract malignancies at Kenyatta National Hospital (KNH) from 1989 ... -
Acceptability of amaranth grain-based nutritious complementary foods with dagaa fish (Rastrineobola argentea) and edible termites (Macrotermes subhylanus) compared to corn soy blend Plus among young children/mothers dyads in Western Kenya
(Canadian Center of Science and Education, 2012-07-02)We assessed acceptability of two flours and porridges of complementary foods based on germinated grain amaranth and maize with or without edible termites and dagaa small fish named “Winfood Classic” (WFC) and “Winfood Lite” ... -
Community perceptions and attitudes on malaria case management and the role of community health workers
(Springer Nature, 2017-07-04)Background Community Case Management of malaria (CCMm) is one of the new approaches adopted by the World Health Organization for malaria endemic countries to reduce the burden of malaria for vulnerable populations. It is ... -
Accept ability of human immunodeficiency virustesting in patients with invasivecervical cancer in Kenya
(Int J Gynecol Cancer, 2006)Invasive cervical cancer (ICC) is common in areas where human immunodeficiency virus (HIV) is also prevalent. Currently, HIV seroprevalence as well as acceptability of HIV testing in ICC patients in Kenya is unknown. The ... -
Endothelial activation biomarkers increase after hiv-1 acquisition: plasma vcam-1 predicts disease progression
(PMC, 2013-07-17)Objective—We aimed to determine whether endothelial activation biomarkers increase after HIV-1 acquisition, and whether biomarker levels measured in chronic infection would predict disease progression and death in HIV-1 ... -
Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya
(Malaria Journal, 2008-09-30)Background: Awareness of the potential impact of malaria among school-age children has stimulated investigation into malaria interventions that can be delivered through schools. However, little evidence is available on the ... -
HIV impact on acute morbidity and pelvic tumor control following radiotherapy for cervical cancer
(Elsevier, 2005-04-13)Objective. To determine the impact of HIV infection on acute morbidity and pelvic tumor control following external beam radiotherapy (EBRT) for cervical cancer. Method. 218 patients receiving EBRT who also had HIV testing ... -
Bancroftian filariasis infection, disease, and specific antibody response patterns in a high and a low endemicity community in East Africa
(The American Society of Tropical Medicine and Hygiene, 2002)Bancroftian filariasis infection, disease and specific antibody response patterns in a high and a low endemicity community in East Africa were analyzed and compared to assess the relationship between these parameters and ... -
Sensitivity of vegetation to climate variability and its implications for malaria risk in Baringo, Kenya
(PLOS ONE, 2018-07-05)The global increase in vector borne diseases has been linked to climate change. Seasonal vegetation changes are known to influence disease vector population. However, the relationship is more theoretical than quantitatively ... -
Mathematical modelling of liver cancer in Western Kenya
(Hikari, 2017)Liver cancer, also known as hepatocellular carcinoma (HCC) is a primary cancer of the liver and the fifth cause of mortality world-wide. It is a global public health problem which is poorly addressed in the developing ... -
Diversity, distribution and abundance of potential rift valley fever vectors in Baringo County, Kenya
(IJMR, 2017)Abstract Rift Valley fever (RVF) is a zoonotic disease that occurs sporadically in form of outbreaks and is transmitted by diverse mosquito species in different geographic regions. Knowledge on diversity, distribution and ...