Red blood cell immune complex binding capacity in children with sickle cell trait (HBAS) living in p. falciparum malaria holoendemic region of Western Kenya

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dc.contributor.authorOtieno, Walter
dc.contributor.authorEstambale, Benson B.
dc.contributor.authorOdera, Michael M.
dc.contributor.authorAluoch, Joash R.
dc.contributor.authorStoute, José A.
dc.date.accessioned2018-06-27T13:21:29Z
dc.date.available2018-06-27T13:21:29Z
dc.date.issued2012
dc.descriptionhttp://www.dtic.mil/dtic/tr/fulltext/u2/a571728.pdfen_US
dc.description.abstractMalaria infection leads to the formation of circulating immune complexes (CICs) which have been implicated in the pathogenesis of complicated malaria which includes severe malarial anemia. Children with sickle cell trait (HbAS) are less predisposed to getting severe manifestations of malaria. We carried out a study to determine the competence of the red blood cells (RBCs) of children with HbAS to bind immune complexes (ICs) and compared this with normal hemoglobin (HbAA).en_US
dc.identifier.urihttp://www.dtic.mil/dtic/tr/fulltext/u2/a571728.pdf
dc.identifier.urihttp://ir.jooust.ac.ke:8080/xmlui/handle/123456789/1341
dc.language.isoenen_US
dc.publisherIJTDHen_US
dc.subjectImmunityen_US
dc.subjectPlasmodium Falciparumen_US
dc.subjectAnemiasen_US
dc.subjectAssayingen_US
dc.subjectChildrenen_US
dc.subjectDeoxygenationen_US
dc.subjectErythrocytesen_US
dc.subjectKenyaen_US
dc.subjectMalariaen_US
dc.subjectPathogenesisen_US
dc.subjectReceptor Sites(Physiology)en_US
dc.subjectSickle Cellsen_US
dc.titleRed blood cell immune complex binding capacity in children with sickle cell trait (HBAS) living in p. falciparum malaria holoendemic region of Western Kenyaen_US
dc.typeArticleen_US

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