2-Hydroxy-4-Methoxybenzaldehyde: larvicidal structure-activity studies
| dc.contributor.author | Mahanga, Geoffrey M. | |
| dc.contributor.author | Akenga, Teresa O. | |
| dc.contributor.author | Lwande, Wilber | |
| dc.contributor.author | Ndiege, Isaiah O. | |
| dc.date.accessioned | 2018-11-20T12:39:53Z | |
| dc.date.available | 2018-11-20T12:39:53Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | 2-Hydroxy-4-methoxybenzaldehyde (1), a compound isolated from Mondia whytei (Hook) Skeels (Asclepiaceae) roots exhibited larvicidal activity (LD5022 mg/mL). A total of 18 other derivatives and closely related congeners revealed varying levels of larvicidal activity. Several closely related congeners, like 2-benzyloxy-4-methoxybenzaldehyde (2), 2-hydroxybenzaldehyde (12), 2-benzyloxybenzaldehyde (3) and benzylphenyl ether (4), showed marked improvement in activity (LD5010, 9, 4.8, 1.2 mg/mL, respectively) against Anopheles gambiae larvae. 2-Benzoyloxy-4-methoxybenzaldehyde (5) exhibited similar activity level (LD50 28 mg/mL) as 1. | en_US |
| dc.identifier.issn | 1011-3924 | |
| dc.identifier.uri | https://www.ajol.info/index.php/bcse/article/view/21110 | |
| dc.identifier.uri | http://ir.jooust.ac.ke:8080/xmlui/handle/123456789/2912 | |
| dc.language.iso | en | en_US |
| dc.publisher | Chemical Society of Ethiopia | en_US |
| dc.subject | 2-Hydroxy-4-methoxybenzaldehyde | en_US |
| dc.subject | Larvicides | en_US |
| dc.subject | Structure-activity relationships | en_US |
| dc.subject | 2-Hdroxybenzaldehyde | en_US |
| dc.subject | 2-Benzyloxybenzaldehyde | en_US |
| dc.subject | Benzylphenyl ether Anopheles gambiae | en_US |
| dc.title | 2-Hydroxy-4-Methoxybenzaldehyde: larvicidal structure-activity studies | en_US |
| dc.type | Article | en_US |